Covid MRNA Vax Detox Protocol
Not Everyone responds the same to the Covid MRNA Vaccinations. Some people have had adverse reactions to the Covid Vax that have left them weak, tired and/or injured. While, we are not "anti-vaccination" in our beliefs, we believe that all known possible treatments should be made available to help the unfortunate people instead of spending time arguing or denying what caused the health issues in the first place.
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It is unknown how many persons have had negative side effects from the Covid vaccinations. VAERS reporting system that tracks adverse reactions and side effects is only used by 25% of the persons affected, it is estimated. Most of the studies available, which are very limited point to PEG in the Covid MRNA vaccinations as the cause for the majority of adverse reactions as it is has been known for years to cause inflammation. Inflammation can lead to the cytokine storm and possibly blood disorders and clotting. Based on research, we want to offer alternative treatments to reduce inflammation and assist in the removal and excretion of the byproduct breakdown of PEG in the body. The proprietary formula we use has been compounded to assist in reducing inflammation, thinning blood with natural ingredients and detoxifying your body. Below are abstract journals about the inflammatory nature of lipid nanoparticles ( PEG) and journals on blood sludging connected to circulating spiked proteins.
GENERALIZED VACCINE DETOX PROTOCOL
In addition to our products listed to assist you in detoxing from the Covid MRNA vaccination, we suggest you supplement your detox with herbal products offered by: Yourbodhi.com.
They sell supplements designed to remove toxins from other vaccinations you have received over the years. According to their sources, " Each vaccine has different ingredients to be aware of, but most contain the same baseline toxins which may harm the body in many ways. It may be hard to believe, but these ingredients are common in all children's vaccinations, flu and other viral vaccines. These ingredients, which can be found on the CDC website, include:
Aluminum, Ammonium, Antibiotics, Artificial Colorings such as Yellow #6 and Phenol Red Dye Bovine Serum (Blood from Cow, Ox, or Buffalo), DNA, Egg Protein, Formaldehyde, Human Serum (Blood Plasma), Canine Kidney (MDCK), Cell Protein, Mercury, Monosodium Glutamate, MRC-5 Cellular Protein (Aborted Fetus Lung Cells), Parasite Cell Protein (Fall ArmyWorm), Preservatives, Thimerosal Sugar (Sucrose)".
Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines
By Dr. Ramya Dwivedi, Ph.D.Mar 15 2021
Lipid nanoparticles (LNPs) are the carrier vehicles that protect messenger RNA (mRNA) molecules from degradation and aid intracellular delivery and endosomal escape in the nucleoside-modified mRNA-LNP vaccine platforms currently used by Pfizer/BioNTech and Moderna, against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These two vaccines surpass the rest with their effective support for T follicular helper cells (Tfh) and the protective humoral responses observed in the preclinical trials.
While the vital role of LNPs in these vaccines' action is established, the potentially inflammatory nature of these LNPs is not assessed. Also, in the Pfizer/BioNTech and Moderna vaccines' human trials, it is reported that side effects often linked to inflammation, such as pain, swelling, fever, and sleepiness, are common.
Because the vaccine was presumed to be non-inflammatory, these side-effects were taken to be generated from the potent immune response to the vaccine. Therefore, there is a need for a systemic approach to analyze the inflammatory properties of LNPs and understand their role in the vaccination process.
In a recent bioRxiv* preprint research paper, Botond Z. Igyártó and colleagues from Thomas Jefferson University demonstrated the inflammatory nature of the lipid nanoparticles (LNPs). Upon intradermal administration in mice, they observed massive neutrophil infiltration, activation of diverse inflammatory pathways, and production of various inflammatory cytokines and chemokines. They observed similar observations when the LNPs were delivered intranasally.
Notably, intranasal inoculation with the same dose (10 μg) of LNP (as in the intradermal delivery) caused a high mortality rate in mice – about 80% of the treated mice died in less than 24 hours. The researchers found that the LNPs' inflammatory properties are not site-specific. They observed a fast diffusion, dispersion, and distribution rate in the tissues, upon internal delivery.
"Thus, the inflammatory milieu induced by the LNPs could be partially responsible for reported side effects of mRNA-LNP-based SARS-CoV-2 vaccines in humans, and are possibly contributory to their reported high potency for eliciting protective immunity."
The LNPs consist of a mixture of phospholipids, cholesterol, PEGylated lipids, and cationic or ionizable lipids. These improve structure, stability and support prolonged circulation. The cationic/ionizable lipids, complex with the negatively charged mRNA molecules and enable the exit of the mRNA from the endosome to the cytosol for translation.
It is reported that some LNPs containing ionizable/cationic lipids are highly inflammatory and possibly cytotoxic. A preclinical study showed adjuvant activity of mRNA complexed with LNPs. To avoid activation of innate inflammatory pathways, in the vaccine, the mRNA is nucleoside-modified.
In this study, the researchers noted that the inflammatory nature of the LNPs could explain their potent adjuvant activity and their superiority, compared to other adjuvants, in supporting the induction of adaptive immune responses.
References
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Pegylated Lipid
The PEGylated lipids of BioNTech/Pfizer and Moderna are 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide (ALC-0159) and polyethylene glycol dimyristoyl glycerol (PEG2000-DMG), respectively [159].
From: Advances in Biomembranes and Lipid Self-Assembly, 2022
3.2.4 Lipid-PEGs used in the COVID-19 Vaccine
As mentioned above, both the BioNTech/Pfizer and Moderna SARS-CoV-2 vaccines use PEGylated LNPs as carriers for the functional mRNA molecules. The PEGylated lipids of BioNTech/Pfizer and Moderna are 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide (ALC-0159) and polyethylene glycol dimyristoyl glycerol (PEG2000-DMG), respectively [159].
ALC-0159 is a synthesized PEGylated lipid used in the BioNTech/Pfizer vaccine formulation. The critical function of ALC-0159 is to provide a protective hydrophilic layer to stabilize lipid-based nanoparticles sterically. The storage stability can be enhanced and non-specific binding to proteins can be reduced [82,160]. On the other hand, PEG2000-DMG is synthesized by PEGylation of myristoyl diglyceride, which is also used to stabilize lipid-based nanoparticles in mRNA vaccines [161,162]. When compared with other PEG-lipids, like PEG2000-DSG, PEG2000-DMG presents faster dissociation from lipid-based nanoparticles, thus shows higher delivery efficacy and shorter circulation time in vivo, and cellular uptake of lipid-based nanoparticles containing PEG2000-DMG may be positively influenced [160,163,164].
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Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
Katrin Knop, Richard Hoogenboom Dr., Dagmar Fischer Prof., Ulrich S. Schubert Prof.
First published: 20 July 2010
https://doi.org/10.1002/anie.200902672
Citations: 2,646
Abstract
Poly(ethylene glycol) (PEG) is the most used polymer and also the gold standard for stealth polymers in the emerging field of polymer-based drug delivery. The properties that account for the overwhelming use of PEG in biomedical applications are outlined in this Review. The first approved PEGylated products have already been on the market for 20 years. A vast amount of clinical experience has since been gained with this polymer—not only benefits, but possible side effects and complications have also been found. The areas that might need consideration and more intensive and careful examination can be divided into the following categories: hypersensitivity, unexpected changes in pharmacokinetic behavior, toxic side products, and an antagonism arising from the easy degradation of the polymer under mechanical stress as a result of its ether structure and its non-biodegradability, as well as the resulting possible accumulation in the body. These possible side effects will be discussed in this Review and alternative polymers will be evaluated.
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The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory
Open AccessPublished:November 19, 2021
Summary
Vaccines based on mRNA-containing lipid nanoparticles (LNPs) are a promising new platform used by two leading vaccines against COVID-19. Clinical trials and ongoing vaccinations present with varying degrees of protection levels and side effects. However, the drivers of the reported side effects remain poorly defined. Here we present evidence that Acuitas' LNPs used in preclinical nucleoside-modified mRNA vaccine studies are highly inflammatory in mice. Intradermal and intramuscular injection of these LNPs led to rapid and robust inflammatory responses, characterized by massive neutrophil infiltration, activation of diverse inflammatory pathways, and production of various inflammatory cytokines and chemokines. The same dose of LNP delivered intranasally led to similar inflammatory responses in the lung and resulted in a high mortality rate, with mechanism unresolved. Thus, the mRNA-LNP platforms' potency in supporting the induction of adaptive immune responses and the observed side effects may stem from the LNPs' highly inflammatory nature.
